首页> 外国专利> Medicine containing inhibitors of leukotrienes natural alone or in combinau00c7u00e7o supplemented with organic selu00canio biodisponu00cdvel for disorders dermatolu00e0gicas hiperproliferativas and their methods terapu00cauticos

Medicine containing inhibitors of leukotrienes natural alone or in combinau00c7u00e7o supplemented with organic selu00canio biodisponu00cdvel for disorders dermatolu00e0gicas hiperproliferativas and their methods terapu00cauticos

机译:包含单独或组合使用的天然白三烯抑制剂的药物,并补充有机sel生物活性剂,用于治疗皮肤性皮肤病,其方法和治疗方法。terap u00cauticos

摘要

Medicine containing inhibitors of leukotrienes natural alone or in combinau00c7u00e7o supplemented with organic selu00canio biodisponu00cdvel for disorders dermatolu00e0gicas hiperproliferativas and their methods terapu00cauticos. The present invention is a product and its use in a method for therapeutic treatment of diseases hiperproliferativas skin, particularly psoriasis skin, scalp and nails.The product includes a dual inhibitor of 5 - lipooxigenase and human leucocyte elastase, alone or in combination with a nutritional supplement of the bioavailable organic selenium.Particularly, the product includes (a) an oral formulation comprising acid, acetyl - 11 - cetobetaboswu00e9lico in combination with bioavailable organic selenium supplement; and (b) a topical formulation comprising acid acetiu00ed - 1 1 - cetobetaboswu00e9lico alone dispersed in a carreado A pharmacist.Proves that the medicine is effective for the therapeutic treatment of psoriasis clinic based on their ability to (I) provide relief of clinical symptoms and (II) the ability to remove psoriatic lesions as evaluated in a phase III clinical study prospective open label And multicentre trial of 3 months.
机译:包含单独或组合使用的天然白三烯抑制剂的药物,并补充有机selbiocandibiodisponcion,可以治疗皮肤性皮肤病和其方法。本发明是一种产品及其在治疗疾病的皮肤,特别是牛皮癣皮肤,头皮和指甲的疾病的方法中的用途。该产品包括5-脂氧合酶和人白细胞弹性蛋白酶的双重抑制剂,单独或与营养组合使用特别地,该产品包括(a)包含酸,乙酰基-11-cetobetabosw ulicelico的酸与生物可利用的有机硒补充剂组合的口服制剂; (b)一种局部制剂,其包含分散在carreado A药剂师中的乙酸-1 1-cetobetabosw u00e9lico。基于其(I)缓解症状的能力,证明该药物可有效治疗牛皮癣。临床症状的评估以及(II)在III期临床研究前瞻性开放标签和3个月的多中心试验中评估的去除银屑病皮损的能力。

著录项

  • 公开/公告号BRPI0800426A2

    专利类型

  • 公开/公告日2009-01-20

    原文格式PDF

  • 申请/专利权人 SABINSA CORPORATION;

    申请/专利号BR2008PI00426

  • 发明设计人 MUHAMMED MAJEED;SUBBALAKSHMI PRAKASH;

    申请日2008-01-21

  • 分类号A61K36/324;A61K31/192;A61K33/04;A61P17/06;

  • 国家 BR

  • 入库时间 2022-08-21 19:28:23

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