TRIPODAL LIGANGS WITH THE COORDINATING MOTIFS K2-BH2 OR K3-BH3 RELEVANT FOR BIOMEDICAL APPLICATIONS OF ORGANOMETALLIC COMPLEXES

摘要

The present invention relates to a compound for use as a chelator in the radioactive labeling of biomolecules with metal tricarbonyl complexes, which compound has the general Formula (I) wherein M is a monovalent cation, such as Li, Na, K, Tl, Rb, Cs or an alkyl ammonium; Rl is H, alkyl, aryl or a biomolecule; R2 is H or a pendant arm, said pendant arm optionally comprises a biomolecule, with the proviso that when Rl is H, R2 is not H or COOH, and when Rl is alkyl or aryl, R2 is not H.