GENETICALLY ENGINEERED L-SORBOSE REDUCTASE-DEFICIENT MUTANTS

摘要

ABSTRACT 288/MAS/99 "Genetically engineered L-sorbose reductase-deficient mutants" The present invention relates to a genetically engineered microorganism derived from a microorganism belonging to the genes Gluconobacter or Acetobacter comprising a gene encoding a protein having L-sorbose reductase activity characterized in that, said gene has a stably integrated mutation and where in said genetically engineered microorganism is deficient in the conversion of L-sorbose to D-sorbitol and wherein the L-sorbose reductase activity within said genetically engineered microorganism is less than 10% of the amount of the activity of the wild-type microorganism.