A PHARMACEUTICAL COMPOSITION FOR TREATING LUNG CANCER, A METHOD FOR INHIBITING GROWTH OR INVASION OF LUNG CANCER AND A METHOD FOR TREATING LUNG CANCER.

摘要

Disclosed herein are a pharmaceutical composition for inhibiting the proliferation or metastasis of lung cancer cells, comprising a substance inhibiting the activity of LlCAM or suppressing the expression of LlCAM, which is a protein present on the surface of lung cancer cells, and a treatment method using the composition. Mouse monoclonal antibodies, recognizing the LlCAM protein on the SCLC cell surface and binding specifically to SCLC tissues, or siRNAs, ant i sense oligonucleotides or shRNAs, may be useful in the treatment of lung cancer by inhibiting the growth, invasion and migration of lung cancer cell.