Delivery method, structure and the composition of nasolacrimal duct system

摘要

The lacrimal point that implantation material is used to be inserted into patient includes a main body. The main body has distal end, proximal end and the axis between it. Body distal end can distad be inserted into the canalicular lumen by the lacrimal point. Main body includes the therapeutic agent contained in pharmaceutical base medicine core. Being exposed to tear agent matrix is discharged into effective therapeutic agent within sustained period in the tear. Ontology has the agent matrix being arranged above a sheath to contain the release and nearly endurance of reagent, which also there is an outer surface to be configured to engagement luminal wall tissue to inhibiting to be discharged, when being disposed therein. In a particular embodiment, agent matrix includes a bioabsorbable polymer, such as silicone resin Inhomogeneous charge object and the agency.