Agent specific Binding to a receptor of platelet derived Growth Factor (PDGFR alpha); Nucleic Acid Molecule that encodes; vector and host Cell comprising combines;That includes the use of Agent and Agent; a

摘要

Targeted binding agents directed to the antigen PDGFR-alpha and uses of such agents are disclosed herein. More specifically the invention relates to fully human monoclonal antibodies directed to the antigen PDGFR-alpha and uses of these antibodies. Aspects of the invention also relate to hybridomas or other cell lines expressing such antibodies. The described targeted binding agents and antibodies are useful as diagnostics and for the treatment of diseases associated with the activity and/or overexpression of PDGFR-alpha.