2-aza-bicycle 2.2.2 octabromodiphenyl ether derivatives for the prevention or treatment of psychosis

摘要

a. A compound from 2-aza-cycle [2.2.2] octabromodiphenyl ether (I), wherein R1 is h or tar (C1-C6);R2 is halogen, CN, alquenilo (C2-C6),-S-tar (C1-C6),-So2nr3r4, wherein R3 and R4 are h or tar (C1-C6), among others;N is 1 to 3. The preferred compounds are: n - (2-azabicolo [2,2,2,2] octan-1-il (phenyl) methyl) - 2,6-dimethylbenzene zamida, N - (2-azabicolo [2,2,2] octan-1-il (phenyl) methyl) - 2,3-dichlorophenyltriamine, N - (2-azabicolo [2,2] octan-1-il (phenyl) - methyl) - 2-chloro-3 - (sulfur trifluoride) benzo-di. He also mentioned a composer of pharmacology These compounds are modulators of glycerol carriers and can be used in the treatment of psychosis, such as schizophrenia, bipolar disorder, Neurodepression, anxiety.