首页>
外国专利>
DEVELOPMENT OF ANIMALS OF CORRUGATED EGGS RECONSTITUTED BY ADULTS OF SOMATIC CELL HARVESTS
DEVELOPMENT OF ANIMALS OF CORRUGATED EGGS RECONSTITUTED BY ADULTS OF SOMATIC CELL HARVESTS
展开▼
机译:体细胞收获成虫重构的波纹蛋的动物研究
展开▼
页面导航
摘要
著录项
相似文献
摘要
Animals are produced following injection of adult somatic cell nuclei into enucleated oocytes. The invention provides a method for cloning an animal by directly inserting at least a portion of the adult somatic nucleus (including the minimum chromosomal material able to support development) into a recipient enucleated oocyte. Preferably, the nucleus is inserted by microinjection and, more preferably, by piezo electrically-actuated microinjection. The oocyte is activated prior to, during, or up to about 6 hours after insertion of the nucleus, by electroactivation or exposure to a chemical activating agent, such as Sr2+. The activated renucleated oocyte is allowed to develop into an embryo and is transplanted to a host surrogate mother to develop into a live offspring.
展开▼