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USE OF ONKOFÖTAL-ANTIGEN SPECIFIC CD4, CD8 CYTOTOXIC, SUPPRESSOR T CELLS AND INTERLEUKIN-10
USE OF ONKOFÖTAL-ANTIGEN SPECIFIC CD4, CD8 CYTOTOXIC, SUPPRESSOR T CELLS AND INTERLEUKIN-10
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机译:肿瘤母细胞抗原CD4,CD8细胞毒,抑制性T细胞和白介素10的使用
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摘要
The present invention provides a method of determining the success of a cancer therapy in an individual, comprising the step of measuring the frequency of occurence of an oncofetal antigen-specific subclasses in the individual's peripheral blood. Also provided is a method of determining whether protective immunity against a tumor will develop in an individual, comprising the step of measuring the frequency of oncofetal antigen-specific T cells, tumor cells and macrophages at the site of the tumor which secrete IL-10. Additionally, a method of determining whether an individual having a tumor will go into remission or remain in remission, comprising the step of measuring the frequency of oncofetal antigen-specific Th1 cells, Tc cells and Ts cells, IL-10 and interferon-gamma secreting T cells in the peripheral blood.
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