RETAILED PIROLO DERIVATIVES (2,1-B) BENZOTIACEPINS WITH ANTIPSYTIC ACTIVITY ATIPICA.

摘要

Compounds of formula (I) ** see formula ** where A is CH-CH2 or C = CH; R is hydrogen, halogen, C 1 -C 4 alkoxy, C 1-C 4 alkylthio, C 1-C 4 alkyl, C 5-C 6 cycloalkyl; R1 is 1-piperazinyl, 1-homopiperazinyl and 1-piperidinyl; R 2 is hydrogen, C 1 -C 4 alkoxy, C 1-C 4 alkylthio, C 1-C 4 alkyl, CHO, CH = NOH, CH 2OH; with the proviso that when R is Cl, A is not C = CH, its individual optical isomers, mixtures thereof and their pharmaceutically acceptable salts.