Transgenic mouse for identification processes and for studies of pharmacodynamic and pharmacokinetic ligand acting on intracellular receptors and method for preparing these.

摘要

A method for producing a transgenic nonhuman mammalian animal, wherein a cassette reporter transgene is incorporated into the genome of said animal, said cassette sequences insulating MAR flanking a reporter transgene ligated to sequences responsive to hormone receptors being composed intracellular, and a constitutive promoter.