Mitogen effect of sonic hedgehog (shh) on precursors of oligodendocytes and their use in demyelinizing diseases. (Machine-translation by Google Translate, not legally binding)

摘要

Sonic hedgehog (shh) mitogenic effect on oligodendrocyte precursors and its use in demyelinating diseases. The present invention relates to the mitogenic effect of sonic hedgehog (shh) protein on oligodendrocyte precursor cells. In particular, and due to said mitogenic effect, the present invention comprises the use of shh for the expansion of oligodendrocyte precursor cells in vitro, as well as their application in the preparation of pharmaceutical compositions for the treatment of demyelinating diseases. (Machine-translation by Google Translate, not legally binding)