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USE OF COMPOSITIONS CONTAINING THE COMBINATION OF ACETAMINOPHEN, ASPIRIN AND CAFFEINE TO ALLEVIATE THE PAIN AND SYMPTOMS OF MIGRAINE
USE OF COMPOSITIONS CONTAINING THE COMBINATION OF ACETAMINOPHEN, ASPIRIN AND CAFFEINE TO ALLEVIATE THE PAIN AND SYMPTOMS OF MIGRAINE
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机译:使用含有醋胺素,阿司匹林和咖啡因的组合物缓解偏头痛的症状和体征
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摘要
The invention provides a safe and economical nonprescription combination ofacetaminophen, aspirin and caffeine (APAP/ASA/CAF)for use in treating migraine pain and the cluster of symptoms characteristicof migraine attack, such as nausea, photophobia, phonophobiaand functional disabilities. In accordance with the present invention, the useof the APAP/ASA/CAF combination is also effective in abortingthe prodrome phase of a migraine attack, prior to the onset of the migraine-associated symptoms, aborting the symptoms of migraine attackprior to the onset of severe, throbbing migraine pain, and aborting migrainepain after a migraine has fully developed. In accordance withthe present invention, the efficacy of the APAP/ASA/CAF combination treatmentin reducing and eliminating migraine pain is at a paritywith the efficacy of sumatriptan, a known, but dissimilar, anti-migraineagent, used at similar dosing regimens. Use of the APAP/ASA/CAFcombination composition treatment at the unit dose also advantageouslyreduces/obviates the need of the migraine sufferer to re-dose orre-medicate at the end of the dosing period in accordance with the presentinvention.
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