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HIGH AFFINITY HUMAN AND HUMANIZED ANTI-a5ß1 INTEGRIN FUNCTION BLOCKING ANTIBODIES WITH REDUCED IMMUNOGENICITY

机译：具有降低免疫原性的高亲和力人类和人类化抗-a5ß1整合功能阻断抗体

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摘要

The present invention relates to recombinant human or humanized polypeptides which bind to a5ß1 integrin with high affinity and blocking function. Further, diagnostic and pharmaceutic applications of the polypeptides are disclosed.

机译：本发明涉及重组人或人源化多肽，其以高亲和力和阻断功能与α5β1整联蛋白结合。此外，公开了多肽的诊断和药学应用。

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公开/公告号WO2007134876A8

专利类型
公开/公告日2009-07-02

原文格式PDF
申请/专利权人 BAYER SCHERING PHARMA AKTIENGESELLSCHAFT;MORPHOSYS AG;MENRAD ANDREAS;WILLUDA JOERG;BOSSLET KLAUS;ZOPF DIETER;PETRUL HEIKE;STEIDL STEFAN;PRASSLER JOSEF;PETIT-FRERE CORINNE;
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申请/专利号WO2007EP04648
发明设计人 MENRAD ANDREAS;WILLUDA JOERG;BOSSLET KLAUS;ZOPF DIETER;PETRUL HEIKE;STEIDL STEFAN;PRASSLER JOSEF;PETIT-FRERE CORINNE;
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申请日2007-05-21
分类号C07K16/28;A01K67/027;A61K39/395;A61P35;C12N15/63;
国家 WO
入库时间 2022-08-21 19:21:50

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