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BIOCOMPATIBLE SCAFFOLD FOR SENSING PROTEINS

机译:可生物相容的传感蛋白支架

摘要

This invention related to a biocompatible scaffold that can detect redox-active chemicals and biomolecules electrochemically. In one embodiment, the biocompatible scaffold includes a substrate, and a conductive layer of Ti?2-containing nanowires or nano fibers formed on the substrate, wherein the conductive layer of Ti?2-containing nanowires or nanofibers is formed with a pore structure, and wherein when the biocompatible scaffold is in contact with a biological analyte, one or more proteins of the biological analyte are immobilized on a surface of the conductive layer Of TiO2- containing nanowires or nanofibers so as to generate a measurable faradic current signal.
机译:生物相容性支架技术领域本发明涉及一种生物相容性支架,其可以电化学检测氧化还原活性化学物质和生物分子。在一个实施方案中,所述生物相容性支架包括基底和形成在该基底上的含Ti 2-2纳米线或纳米纤维的导电层,其中所述含Ti 2-2纳米线或纳米纤维的导电层形成为具有孔结构,并且其中当所述生物相容性支架与生物分析物接触时,所述生物分析物的一种或多种蛋白质被固定在包含TiO 2的纳米线或纳米纤维的导电层的表面上,以产生可测量的法拉第电流信号。

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