METHODS AND COMPOSITIONS FOR INHIBITING TOLL-LIKE RECEPTOR MEDIATED IMMUNE RESPONSES

摘要

The present invention provides compounds that are useful in inhibiting signaling activities mediated by Toll-like receptors. The invention also provides therapeutic methods for treating or preventing various diseases or disorders associated with or mediated by aberrant TLR signaling activities. Further provided in the invention are methods of screening for TLR antagonist compounds with improved properties.