HEPATOCELLULAR CARCINOMA PROTEIN MARKER, AND METHOD FOR DETECTION OF HEPATOCELLULAR CARCINOMA USING THE SAME

摘要

Disclosed is a method for determining the presence of hepatocellular carcinoma by using a protein that takes a different phosphorylation modification state in a hepatocellular carcinoma cell from that in a non-hepatocellular carcinoma cell. Also disclosed is a hepatocellular carcinoma protein marker for use in the detection of hepatocellular carcinoma, which comprises the protein. Specifically disclosed is a hepatocellular carcinoma protein marker for use in the detection of hepatocellular carcinoma, which comprises a tumor rejection antigen gp96 having an amino acid sequence depicted in SEQ ID NO: 1. The hepatocellular carcinoma protein marker enables to detect the presence of hepatocellular carcinoma by measuring the phosphorylation modification state.