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PEPTIDE GACFSIAHECGA FOR TARGETING MTL-MMP
PEPTIDE GACFSIAHECGA FOR TARGETING MTL-MMP
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机译:肽GACFSIAHECGA用于靶向MTL-MMP
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摘要
The present invention relates to peptid es comprising the amino acid sequence C X1 X 2 X3 X4 X5 X6 C wherein C is cysteine, X1 is Phenylalanine, X2 is Serine, X3 is Isoleusine, X4 is Alanine, X5 is Histidine, X6 is Glutamic acid, or a conservative an alogue of any or each of the amino acids. The peptides are useful as inhibitors of MT1-MMP activity and/or are capable of targeting to a cell or cells ha ving enhanced MT1-MMP activity.
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机译:本发明涉及包含氨基酸序列C X1 X 2 X3 X4 X5 X6 C的肽,其中C为半胱氨酸,X1为苯丙氨酸,X2为丝氨酸,X3为异亮氨酸,X4为丙氨酸,X5为组氨酸,X6为谷氨酸,或任何或每个氨基酸的保守类似物。所述肽可用作MT1-MMP活性的抑制剂和/或能够靶向具有增强的MT1-MMP活性的细胞。
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