METHOD FOR SCREENING FOR SELECTIVE MODULATOR OF THE NF-?B PATHWAY ACTIVATION

摘要

The invention relates to methods for screening for selective modulator of NF-?B pathway activation. The invention concerns methods for primary screening molecules that potentially modulate (activate or inhibit) the NF-?B pathway activation by identifying and selecting molecules modulate the interaction of NEMO with other proteins. The invention also concerns methods for secondary screening for modulator (activator or inhibitor) of the NF-?B pathway activation.