VASCULAR MARKERS IN THE REMODELLING OF CARDIAC INJURY

摘要

The present invention is concerned with diagnostic means and methods. More specifically, the present invention relates to a method for diagnosing the angiogenic status of a subject suffering from myocardial infarction comprising determining the amounts of PLGF, sFLT1 and Endoglin in a first sample of a subject obtained after myocardial infarction and in a second sample of the said subject obtained after the said first sample and comparing the said amounts in the first sample with those in the second sample whereby the angiogenic status is diagnosed. The present invention also encompasses a method of determining whether a subject suffering from myocardial infarction is susceptible to a pro-angiogenic therapy. Finally, the present invention relates to a kit or a device for carrying outthe method of the invention.