首页>
外国专利>
TEST METHOD RELATING TO ADIPOSE CELLS AND TO OBESITY BY USING A HUMAN H-PGDS OVEREXPRESSING NON-HUMAN ANIMAL
TEST METHOD RELATING TO ADIPOSE CELLS AND TO OBESITY BY USING A HUMAN H-PGDS OVEREXPRESSING NON-HUMAN ANIMAL
展开▼
机译:通过过表达非人类动物的人H-PGDS来进行脂肪细胞和肥胖相关的测试方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present application provides a human gene over-expressing animal, which is a non-human animal carrying a human hematopoietic prostaglandin D2 synthase gene in its somatic cell chromosome and expressing a large amount of human prostaglandin D2 synthase, wherein the animal is one obtained through ontogenesis of a totipotency cell of a non-human animal or offspring of the obtained animal, and the totipotency cell is introduced with said synthase gene. The present application also provides a method of using the transgenic animal for testing in vivo activity of a candidate for anti-allergy medicines, sleep-controlling substances and candidates for anti-obesity.
展开▼