DOUBLE-LAYERED-HOLLOW MEMBRANE FOR BIOREACTOR APPLICATIONS

摘要

Carrier membrane for biohybridorgane and biohybridreaktoren with a two layer - membrane wall, the layers of different polymers or polymer blends, a surface of which is compatible with blood, while its other surface and the layers of fabric is compatible with the formation of a structural integrity adhere to each other, obtainable by a first polymer solution, which contains a blood compatible polymer, and a second polymer solution, which contains a tissue compatible polymer, separately from one another by release of the respective polymer in a solvent be produced in such a way that both polymer solutions in the form of polymer solutions remain mixture in a homogeneous state, the two polymer solutions in the nozzle of an extruder to each other to form a layer-like polymer solution are brought into contact, the collar and at the same time, in this form as polymer solution collar from the nozzle of the extruder be added to the extrusion, the polymer solution is extruded in a coagulation bath and is subjected to a phase inversion and the two layer - membrane of all not - membrane-forming components and, if necessary, at least partly freed is aftertreated.