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PROSTAGLANDIN F2 ALPHA ANALOGS IN COMBINATION WITH ANTIMICROBIAL FOR TREATING GLAUCOMA
PROSTAGLANDIN F2 ALPHA ANALOGS IN COMBINATION WITH ANTIMICROBIAL FOR TREATING GLAUCOMA
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机译:前列腺素F2α类似物与抗微生物药联合治疗青光眼
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摘要
An ophthalmic formulation for the treatment of glaucoma and intraocular pressure with a prostaglandin compound of the F-series (PGF), and particularly a prodrug form of a PGFSUB2alpha/SUB analog, such as an ester, amide, or internal lactone, wherein preservative is an antimicrobial peptide, such as lactoferrin. In particularly preferred embodiments, the prostaglandin compound is a macrocyclic internal 1,15-lactone, such as the 16-aryloxy prostaglandin analogs, illustratively fluprostenol or cloprstenol.
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