COMPOSITIONS AND METHODS FOR PREVENTION OF INFECTION IN TRANSCUTANEOUS OSSEOINTEGRATED IMPLANTS

摘要

This invention relates to a method of preventing wound infection by administering a therapeutic formulation comprising a peptide to a wound site. More specifically, the invention relates to the use of amphiphilic peptides in preventing and treating infections. The invention also relates to preventing wound infectionin a host by administering a biologically active amphiphilic peptide or biologically active protein to a host having a wound wherein the peptide or protein is administered in an amount effective to prevent wound infection. Even more specifically the invention relates to the use of cationic amphiphilic peptides in preventing and treating infections associated with transcutaneous osseointegreated implants.