首页> 外国专利> PYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE CCR5 RECEPTORS

PYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE CCR5 RECEPTORS

机译:吡咯啉衍生物作为趋化因子CCR5受体的调节剂

摘要

The present invention provides compounds of formula (I) wherein R1 to R6 and m are as defined hereinabove. The compounds of the present invention are modulators, especially antagonists, of the activity of chemokine CCR5 receptors. Modulators of the CCR5 receptor may be useful in the treatment of various inflammatory diseases, autoimmune diseases, pain, and. in the treatment of infection by HIV and genetically related retroviruses.
机译:本发明提供了式(I)的化合物,其中R 1至R 6和m如上所定义。本发明的化合物是趋化因子CCR5受体活性的调节剂,尤其是拮抗剂。 CCR5受体的调节剂可用于治疗各种炎性疾病,自身免疫性疾病,疼痛和。用于治疗HIV和遗传相关逆转录病毒的感染。

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