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New version kolde Leah's multi-borane lg 31-3 strain, amidase and methods for the optical resolution of the racemic mixture using the above amidase produced therefrom
New version kolde Leah's multi-borane lg 31-3 strain, amidase and methods for the optical resolution of the racemic mixture using the above amidase produced therefrom
The present invention relates to novel member kolde Ria multi borane's strains, amidase (amidase), and relates to the optical resolution (optical resolution) method of the racemic mixture using the above amidase (amidase), and more particularly, server produced therefrom kolde Leah's multi-borane LG 31-3 (Burkholderia multivorans LG 31-3) strain, the present invention relates to an optical resolution method of a racemic mixture using an amidase (amidase), and the amidase with the stereoselective substrate specificity. ; The present invention to a new version kolde Ria multi borane bus LG 31-3 strain (KCTC 10920BP) amidase which is produced from the optical resolution can be easily referred to a racemic mixture under the enzymatic reaction conditions of high ambient temperature and pressure for a single optical isomer according It can be prepared in purity. ; Amidase, server kolde Ria multi borane switch, an optical resolution, (S) -2- (4-chlorophenyl) -3-methylbutyric acid
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机译:本发明涉及新成员金多氏菌属多硼烷菌株酰胺酶(酰胺酶),并且涉及使用上述酰胺酶(酰胺酶)的外消旋混合物的旋光拆分(光学拆分)方法,更具体地讲,由科尔德利亚生产的服务器硼烷 LG I> 31-3(伯克霍尔德菌 multivorans I> LG 31-3)菌株,本发明涉及使用酰胺酶(酰胺酶)的外消旋混合物的旋光拆分方法和酰胺酶具有立体选择性底物特异性。 ;由光学分辨率产生的新版本的kolde Ria多硼烷总线LG 31-3菌株(KCTC 10920BP)酰胺酶的本发明可以在高环境温度和压力的酶促反应条件下容易地称为外消旋混合物,以用于分离。可以根据纯度制备单一旋光异构体。 ;酰胺酶,服务器kolde Ria多硼烷开关,光学分辨率,(S)-2-(4-氯苯基)-3-甲基丁酸
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