ALGINATE PARTICLE CONTAINING CALCIUM CARBONATE IN MATRIX AND THE METHOD FOR PRODUCTION OF THE SAID ALGINATE PARTICLE

摘要

An alginate particle containing calcium carbonate in matrix is provided to selectively release the various hydrophobic and hydrophilic physiological ingredients within the particle by releasing the relatively small amount of target material encapsulated at basic pH and the relatively large amount of target material encapsulated at acidic pH. The alginate particle contains calcium carbonate in alginate matrix, and is prepared by mixing solution or suspension containing alginate and the target material with solution or suspension containing calcium carbonate to prepare calcium carbonate-alginate mixed solution, and adding droplet of or spraying the calcium carbonate-alginate mixed solution into multivalent cation solution.