THE BIOMARKER FOR DIAGNOSIS OF INTRAHEPATIC CHOLESTASIS AND THE METHOD OF DIAGNOSIS FOR INTRAHEPATIC CHOLESTASIS THEREOF

摘要

The present invention relates to a biomarker for diagnosing intrahepatic bile stagnation and a method for diagnosing intrahepatic bile stagnation using the same, by measuring a gene expression change using a microarray chip in an animal model in which paloidine is administered and intrahepatic bile stagnation is induced, By confirming that the expression is changed, the changed genes can be used as a biomarker for diagnosing intrahepatic bile stagnation, and can also be usefully used for diagnosing intrahepatic bile stagnation using the biomarker.;Intrahepatic Cholestasis, Paloidine, Biomarkers, Microarray Chips