MARKER GENES BASED ON DAUNORUBICIN TREATMENT FOR SCREENING OF DRUG INDUCING CARDIO TOXICITY AND SCREENING METHOD USING THEREOF

摘要

The present invention relates to a marker gene for cardiovascular toxicity-inducing drug search and a search method using the same, and more particularly, to a marker gene in which gene expression is increased or decreased by cardiovascular toxicity-inducing drug Daunorubicin, and a cardiovascular system using the same. The present invention relates to a method of searching for a toxic drug. The marker gene of the present invention can be usefully used for monitoring and determining drugs or chemicals having a risk of cardiovascular toxicity by using the response genes selected through the DNA microarray chip as marker genes. It can be used as a tool to identify mechanisms of action that cause side effects.;Daunorubicin, marker gene, microarray, cardiovascular toxicity