PATCH COMPOSITIONS BEING CAPABLE OF PHASE TRANSITION AT BODY TEMPERATURE AND IMPROVING SKIN ELASTICITY, MOISTURIZATION AND DRUG PENETRATION AND ITS MANUFACTURING METHOD THEREOF

摘要

A novel patch composition which forms a gel patch by phase transition from liquid to gel is provided to prevent evaporation and ensure moisturization, skin elasticity and drug transmission. A patch composition enhancing skin elasticity, moisturizing, drug penetration comprises: 40.0-75.0 weight part of water, 2.0-10.0 weight part of water soluble moisturizer, 5.0-30.0 weight part of polymer surfactant, 0.1-5.0 weight part of powder phase moisturizer, 0.01-3.0 weight part of powder type physiology activation substance, 0.01-10.0 weight part of physiology activation substance. A method for manufacturing the patch composition which turns from liquid phase to gel phase by the body temperature: a step of cooling 40.0-75.0 weight part of water and 2.0-10.0 weight part of water soluble moisturizer to 15°C-0°C, adding and resolving 5.0-30.0 weight part of polymer surfactant to obtain a first mixture; a step of resolving 0.1-5.0 weight part of moisturizer and 0.01-3.0 weight part of powder phase physiology activation substance in the first mixture to obtain a second mixture; and a step of adding 0.01-10.0 weight part of physiology activation substance in the second mixture to obtain the patch composition.