Apparatus and method for giving an organism pathway name using Gene Homologue information

摘要

An apparatus and a method for assigning a bio pathway of a gene list by using gene homologue information are provided to enable a chip analyzer to determine a function of a cluster easily by automatically giving a bio pathway name of a gene cluster list resulted from clustering chip experiment data. An apparatus for assigning a bio pathway of a gene list includes a homologue/uniqueness gene list generator(110), a vocabulary assigning unit(120), a statistical similarity probability calculator(130) and a pathway assigning unit(140). The homologue/uniqueness gene list generator generates a homologue or uniqueness gene list by selecting genes owned and not owned by a comparison species among a gene list of a target species. The vocabulary assigning unit assigns vocabularies of a GO(Gene Ontology) and a KEGG(Kyoto Encyclopedia of Genes and Genomes) to the homologue/uniqueness gene list. The statistical similarity probability calculator calculates hyper geometric distribution similarity probability in the homologue/uniqueness gene list for each vocabulary of the GO and the KEGG. The pathway assigning unit selects the vocabulary of the GO and the KEGG having the minimum hyper geometric distribution similarity probability for each gene list, and assigns the selected vocabulary to the bio pathway name.