DRY POWDER INHALATION DEVICE FOR TRANSPULMONARY ADMINISTRATION

摘要

Dry powder inhalation system contains a single dose of active ingredient and comprises a combination of a container packed with a freeze-dried composition in the form of a non-powder cake, which upon an air impact, disintegrates into fine particles, with a device having a means of imparting air impact to the freeze-dried composition in the container and a means of discharging fine particles. Dry powder inhalation system contains a single dose of active ingredient and comprises a combination of a container packed with a freeze-dried composition in the form of a non-powder cake, having a decay index of at least 0.015 and upon an air impact having an air speed of at least 1 m/second and an air flow rate of at least 17 ml/second, disintegrating into fine particles having an average particle diameter of upto 10 mu m or an effective particle ratio of at least 10%, with a device having a means of imparting the air impact to the freeze-dried composition in the container and a means of discharging the powdery freeze-dried composition disintegrated into fine particles from the container.