METHOD OF ESTIMATION OF THE DEGREE OF THE GRAVITY OF THE STATE AND PREDICTION OF THE OUTCOME OF PATIENTS DISEASE WITH THE URGENT SURGICAL PATHOLOGY OF ORGANS OF THE ABDOMINAL CAVITY

摘要

A method for assessing the degree of severity of a condition and predicting the outcome of a disease in patients with urgent surgical abdominal pathology including an assessment of the state of the abdominal organs according to the Mannheim index of peritonitis, the severity of the SAPS II score, the determination of the absolute amount in μl of peripheral blood CD3 +, CD4 +, CD8 + CD16 +, CD20 + lymphocytes, CD38 + / CD95 +, CD25 + / CD38 +, CD25 + / CD95 + ratios, which is characterized by the use of IIP, SAPS II, absolute CD20 + lymphocyte count, CD38 + / CD95 +, CD25 + / CD38 + , CD25 + / CD95 +, as well as the distance from the center of the immune system cluster to calculate the severity of the patient's condition according to the formula T = 0.090 + 0.108 · b + 0.130 · b + 0.086 · b + 0.068 · b + 0.133 · b0.076 · b-0.001 · DK , where TC is the severity of the patient's condition, b- scoring of the abdominal cavity on the basis of the Mannheim index of peritonitis, b- score of the patient's severity based on the SAPS II scale, b- score of the CD20 counts, lb-score of the CD38 + and CD95 + lymphocyte ratios, b- score of the CD25 + and CD38 + lymphocytes, b- score ratio of CD25 + and CD95 + lymphocytes, DC - distance from the center of the immune status cluster, individual calculation of the probability of a lethal outcome in percent is carried out according to the power-function formula, EMI = 7.446 · TC-75.551 · TC + 266.261 · TC-379.511 · TC +22 9,489 · TC-49,025, where VLI is the probability of death, expressed as a percentage, and TC is the severity of the patient's condition.