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PHARMACEUTICAL COMPOSITIONS, INCLUDING NEP (NEUTRAL ENDOPEPTIDASE) INHIBITORS, ENDOGENOUS PRODUCING ENDOTHELIN INHIBITORS AND HMG (Hydroxytromide) Inhibitors
PHARMACEUTICAL COMPOSITIONS, INCLUDING NEP (NEUTRAL ENDOPEPTIDASE) INHIBITORS, ENDOGENOUS PRODUCING ENDOTHELIN INHIBITORS AND HMG (Hydroxytromide) Inhibitors
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机译:药物组合物,包括NEP(中性内肽酶)抑制剂,内源性内皮素抑制剂和HMG(羟脯氨酸)抑制剂
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摘要
A combination therapy is disclosed for treating or inhibiting cardiovascular or metabolic diseases or conditions through a combination of at least one inhibitor of neutral endopeptidase (=NEP), at least one inhibitor of the endogenous endothelin producing system and at least one HMG CoA reductase inhibitor. Pharmaceutical compositions are also described comprising NEP inhibitors, inhibitors of the endogenous endothelin producing system and HMG CoA reductase inhibitors and the use of these pharmaceutical composition in the prophylaxis or treatment of cardiovascular and/or metabolic disorders or diseases in mammals (including humans).
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