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Ways of assessing the safety of products for human health and determining the integral of acceptable risk INDIVIDUAL CLASSES AND COMMODITIES HEALTH

机译:评估产品对人体健康的安全性和确定可接受风险的组成部分的方法个人类别和商品健康

摘要

FIELD: medicine.;SUBSTANCE: inventions relate to medicine, in particular to investigation and registration of human health disorders as response to impact of various products. Basing on retrospective statistic analysis mean annual number of citizens' health disorders caused by all types of products is determined and they are classified by types in accordance with degree of health disorder severity. Simultaneously, in accordance with discrete intervals, value from zero to one is given to each stated degree by reference interval scale. Further, taking into account error amount for each type of mean annual number of health disorders in accordance with said severity degree and, using coefficient 1/70, which is selected from value of 70 years, characterising average human life span, and also using value 5%, characterising permissible annual increase of health disorders on the whole without impermissible increase of background indices, permissible risk Rintperm of total production - all classes of products, for citizens' health is calculated. Then integral permissible risk Riperm of separate classes of products for human health, integral permissible risk Rjperm for separate types of products are determined.;EFFECT: method allows to obtain reliable evaluation of integral permissible risk of separate classes and types of products for human health due to extension of taken into account gradation of citizens' heath disorder by reference integral scale of severity degree of said disorder.;2 cl; 2 tbl, 2 ex
机译:领域:药物;发明:发明涉及医学,尤其涉及人类健康疾病的调查和注册,以响应各种产品的影响。根据回顾性统计分析,可以确定由所有类型的产品引起的公民健康疾病的年度数量,并根据健康疾病严重程度对疾病进行分类。同时,根据离散间隔,通过参考间隔标度为每个指定的度赋予从零到一的值。此外,考虑与所述严重程度相对应的每种类型的年平均健康疾病的误差量,并使用从70岁的值中选择的系数1/70,表征平均人类寿命,并且还使用值5%,特征是总体上健康疾病每年允许增加,而背景指数没有允许增加,总生产量(所有产品类别)的允许风险R int perm 健康是经过计算的。然后是针对人类健康的不同类别产品的总允许风险R i perm ,总允许风险R j perm 确定效果;方法:方法允许获得可靠的评估,用于评估不同类别和类型的产品对人类健康的整体允许风险,这是由于参考了严重程度参考的整体健康等级对公民健康障碍的等级进行了扩展所述疾病的程度。; 2 cl; 2汤匙,2前

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