首页> 外国专利> APPLICATION OF COMPLEX IRON (III) COMPOUNDS FOR PRODUCTION OF MEDICINE FOR ORAL TREATMENT OF IRON DEFICIENCY CONDITIONS IN PATIENTS AFFECTING CHRONIC INFLAMMATORY DISEASES OF THE INTESTINE

APPLICATION OF COMPLEX IRON (III) COMPOUNDS FOR PRODUCTION OF MEDICINE FOR ORAL TREATMENT OF IRON DEFICIENCY CONDITIONS IN PATIENTS AFFECTING CHRONIC INFLAMMATORY DISEASES OF THE INTESTINE

机译:复杂铁(III)化合物在生产治疗肠道慢性炎症性疾病的铁缺乏症患者中的应用

摘要

1. The use of a complex compound of iron (III) with a carbohydrate for the manufacture of a medicament for oral treatment of iron deficiency conditions in patients suffering from chronic inflammatory bowel disease. ! 2. The use according to claim 1, in which the carbohydrate is selected from the group consisting of dextrans and hydrogenated dextrans, dextrins and hydrogenated or oxidized dextrins, as well as pullulan, its oligomers and hydrogenated pullulan. ! 3. The use according to claim 1, in which the carbohydrate is selected from oxidized or hydrogenated dextrins. ! 4. The use according to claim 1, in which the complex compound of iron (III) is a complex compound of iron (III) -polymaltose. ! 5. The use according to claim 4, in which the complex compound iron (III) -polymaltose has a molecular weight in the range from 20,000 to 500,000 D.! 6. The use according to claim 1, in which the complex compound of iron (III) is a complex compound of iron (III) with the oxidation product of one or more maltodextrins. ! 7. The use according to claim 6, in which the complex compound of iron (III) is a water-soluble iron-carbohydrate complex obtained from an aqueous solution of an iron (III) salt and an aqueous solution of the oxidation product of one or more maltodextrins with an aqueous solution of hypochlorite at a pH of alkaline region, and in which, if maltodextrin is used alone, then its dextrose equivalent is from 5 to 37; if a mixture of several maltodextrins is used, then the dextrose equivalent of the mixture is from 5 to 37, and the dextrose equivalent of the individual maltodextrins included in the mixture is from 2 to 40.! 8. The use according to claim 1, in which the drug
机译:1.铁(III)与碳水化合物的复合化合物在制备用于口服治疗慢性炎性肠病患者铁缺乏症的药物中的用途。 ! 2.根据权利要求1的用途,其中所述碳水化合物选自右旋糖酐和氢化右旋糖酐,糊精和氢化或氧化的糊精,以及支链淀粉,其低聚物和氢化支链淀粉。 ! 3.根据权利要求1的用途,其中碳水化合物选自氧化或氢化糊精。 ! 4.根据权利要求1的用途,其中铁(III)的络合物是铁(III)-聚麦芽糖的络合物。 ! 5.根据权利要求4的用途,其中所述复合化合物(III)-聚麦芽糖的分子量为20,000至500,000D。 6.根据权利要求1的用途,其中铁(III)的络合物是铁(III)与一种或多种麦芽糊精的氧化产物的络合物。 ! 7.根据权利要求6的用途,其中铁(III)的配合物化合物是从铁(III)盐的水溶液和一种的氧化产物的水溶液获得的水溶性铁-碳水化合物配合物。或更多的麦芽糖糊精与pH值处于碱性区域的次​​氯酸盐水溶液混合,如果单独使用麦芽糖糊精,则其葡萄糖当量为5至37;如果使用几种麦芽糖糊精的混合物,则混合物的右旋糖当量为5至37,混合物中所含单个麦芽糖糊精的右旋糖当量为2至40。 8.根据权利要求1的用途,其中药物

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