Micro - and nano fluid system for dynamic structural analysis of linear of macromolecules and uses thereof

摘要

Fluidic systems in the micro - and nano range, as a chip in the modem biology laboratories and biochemistry, in particular in the case of the analysis of frequently often complex folded linear macromolecules (lm) used such as, for example, dna. For the analysis of these must by means of a transport fluid (fl) to entropic barriers (eb), electromagnetically irradiated and the transmission response is to be evaluated. Deployment and irradiation, it has been carried out in separate process steps and structures. The new micro - and nano fluid system (ns) is characterized by a spatial and temporal combination of the deployment in a fluid channel (fk) and an irradiation channel (bk) in a photonic crystal (pk), i.e, a spatially periodic lattice structure (pg) with the grid openings (go), whose extension on the deployment of the passing through linear macromolecules (lm) are adapted, and by means of the spectral range. The lattice structure, for example, as a nano columns field (nf) be designed. As an integrated system on a common substrate, such micro - and nano fluid systems (ns) complex functions, for example as the microwave bioreactor (mb) for the cell-free protein biosynthesis with a reaction chamber (rr) between two photonic crystals (pk1, pk2) and, if desired, with further devices for additional process steps.