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Hyaluronic acid and alpha -, beta - poly aspartyl hydrazide hydro gels and the biomedical and pharmaceutical applications
Hyaluronic acid and alpha -, beta - poly aspartyl hydrazide hydro gels and the biomedical and pharmaceutical applications
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机译:透明质酸和α-,β-聚天冬氨酰肼水凝胶以及生物医学和制药应用
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摘要
Compositions and products based on the chemical crosslinking of hyaluronic acid with a polyfunctional polymer having a protein-like structure, bearing hydrazido pendent groups along the polymeric chain. The polymer is preferably, alpha-beta-polyaspartylhydrazide, a biocompatible macromolecule. The materials obtained after crosslinking, specifically hydrogels, undergo a reduced chemical and enzymatic degradation, unlike the starting hyaluronic acid, and they can be used to prepare systems for applications in the biomedical and pharmaceutical field.
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