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an immune response triggering composition with nanoparticles based on a methylvinylether - maleic acid - copolymers

机译:具有基于甲基乙烯基醚-马来酸-共聚物的纳米粒子的免疫反应触发组合物

摘要

The composition for stimulating an immune response in a subject comprises methyl vinyl ether and maleic anhydride copolymer-based nanoparticles. Said nanoparticles may further contain an allergen or an antigen and/or an immunostimulating agent, which may be contained inside said nanoparticles and/or at least partially coating the surface of said nanoparticles, and optionally a cross-linking agent. The immune response stimulating composition is useful as an adjuvant in immunotherapy and vaccines.
机译:用于刺激受试者的免疫应答的组合物包含甲基乙烯基醚和基于马来酸酐共聚物的纳米颗粒。所述纳米颗粒可以进一步包含变应原或抗原和/或免疫刺激剂,其可以包含在所述纳米颗粒内部和/或至少部分地涂覆所述纳米颗粒的表面,以及任选地交联剂。刺激免疫应答的组合物可用作免疫疗法和疫苗中的佐剂。

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