首页> 外国专利> LIPID A ANTAGONISTS WITH ANTI-SEPTICAL SHOCK EFFECT, ANTI-CHEMICAL EFFECT AND ANALYTICAL EFFECT

LIPID A ANTAGONISTS WITH ANTI-SEPTICAL SHOCK EFFECT, ANTI-CHEMICAL EFFECT AND ANALYTICAL EFFECT

机译:具有抗冲击作用,抗化学作用和分析作用的脂类拮抗剂

摘要

The present invention relates to compounds of general formula (I), wherein RSUB1/SUB-RSUB4/SUB are as defined in the description, to processes for their preparation and to their use as medicaments. The compounds of formula (I) inhibit the effect of lipid A on the Toll-like Receptor 4 and are endowed with anti-septic shock, anti-inflammatory, anti-ischemia and analgesic activity.
机译:本发明涉及通式(I)的化合物,其制备方法及其用途,其中R 1 -R 4 如说明书中所定义。药物。式(I)化合物抑制脂质A对Toll样受体4的作用,并具有防腐休克,抗炎,抗局部缺血和止痛活性。

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