Manufacture of a neolignans by means of ddq mediated dimerization of dihydroasaron

摘要

The present invention relates to a novel neolignan (NEOLASA-I) 3-ethyl-2-methyl-3-(2', 4', 5'-trimethoxy-phenyl-1-(2',4',5'-trimethoxy) phenyl-1-(2',4',5'-trimethoxy)phenyl-1-propene and a process for the preparation of high purity, higher yield neolignan, a-asarone, 2,4,5-trimethoxy-phenyl propionone from b-asaroneor b-asarone rich Acorus calamus oil containing a and g - asarone by hydrogenating and dimerizing by treatment with DDQ in presence of an organic acid.