PROCEDURES FOR THE PURPOSE OF A RISK OF AN ACID-ASSOCIATED CANCER IN AN INDIVIDUAL

摘要

The present invention is directed to a method for detecting a risk of gastric acid related disease in an individual based on assaying the analytes pepsinogen I, fasting gastrin-17 and a marker for Helicobacter pylori infection (Hp-marker), the method comprising selecting a cut-off value for pepsinogen I, fasting gastrin-17 and the Hp-marker, determining the concentration of pepsinogen I, fasting gastrin-17 and the concentration or presence of a Hp-marker in a sample from said individual, andcomparing the concentrations so determined with the selected cut-off values, whereby a pepsinogen I value at or above its respective cut-off value in combination with a Hp-marker value below its respective cut-off value and a fasting gastrin-17 value at or below its cut-off is indicative of an increased risk of gastric acid-related disease in said individual.