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DERIVATIVES OF GOSSYPOL AND APOGOSSYPOL, THEIR PREPARATIONS AND THEIR APPLICATIONS
DERIVATIVES OF GOSSYPOL AND APOGOSSYPOL, THEIR PREPARATIONS AND THEIR APPLICATIONS
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机译:古斯波夫和罗汉果的衍生物,其制备方法和应用
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摘要
Derivatives of gossypol and apogossypol of general formula (1) in which R1b and R'1b are each independently a linear or branched alkyl of 1 to 6 carbon atoms optionally substituted, a linear or branched alkoxy of 1 to 6 carbon atoms optionally substituted, or an ester, R2b and R'2b are each independently a linear or branched alkyl of 1 to 6 carbon atoms optionally substituted, a linear or branched alkoxy of 1 to 6 carbon atoms optionally substituted, or an ester , R3 and R '3 are each independently hydrogen or CHO or any group capable of being converted in vivo to liberate hydrogen or CHO, R4, R'4, R5, R'5, R6 and R'6 are each independently hydrogen, a linear or branched alkyl of 1 to 6 carbon atoms optionally substituted, or a group protecting the hydroxy function, gossypol and apogossypol being excluded, or one of its enantiomers, or a salt thereof, or a salt of one of its enantiomers; pharmaceutical composition containing said compound; plant protection composition containing the said optionally substituted carbon compound, or a group protecting the hydroxy function, gossypol and apogossypol being excluded, or one of its enantiomers, or a salt thereof, or a salt of one of its enantiomers ; pharmaceutical composition containing said compound; phytopharmaceutical composition containing said compound.
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