SUBSTITUTED SULFONAMIDE COMPOUND AND ITS METHOD OF APPLICATION AS MEDICINE FOR TREATMENT OF CNS DISORDER, OBESITY, AND DIABETES MELLITUS TYPE 2

摘要

PPROBLEM TO BE SOLVED: To provide a medicine having 5-HT6 receptor antagonist activity and useful for prevention and treatment of obesity, diabetes mellitus type 2 and/or central nervous system disorder. PSOLUTION: The substituted sulfonamide compound is represented by general formula (I) (wherein P is a sulfonamide or amide-substituted sulfonic acid, provided that P and RSP3/SPare mutually allocated at meta- or para-position; RSP3/SPis piperazine, 1,4-diazepan, etc.; ring A-B is naphthalene, isoquinoline, quinoline, 1,7-naphthyridine, benzofuran, etc.). PCOPYRIGHT: (C)2010,JPO&INPIT