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HAPTEN-CARRIER CONJUGATE FOR USE IN CURE FOR DRUG ABUSE AND PREPARING METHOD THEREFOR

机译:用于药物滥用治疗的半抗原载体缀合物及其制备方法

摘要

PPROBLEM TO BE SOLVED: To provide a hapten-carrier conjugate that can bring out an anti-hapten antibody in vivo. PSOLUTION: The hapten-carrier conjugate is represented by the formula (wherein, A, B, C, D, E and F are each a side chain of nicotine; these are independent and at least one of these indicates a carrier such as cholera toxin B (CTB) containing at least one T-cell epitope). When the hapten is a substance to cause poisoning, a composition for curing containing the hapten-carrier conjugate is especially useful for treatment of poisoning. PCOPYRIGHT: (C)2010,JPO&INPIT
机译:

要解决的问题:提供一种可以在体内产生抗半抗原抗体的半抗原-载体偶联物。

解决方案:半抗原-载体共轭物由下式表示:(其中,A,B,C,D,E和F分别为尼古丁的侧链;它们是独立的,并且至少有一个表示载体,例如如霍乱毒素B(CTB),含有至少一个T细胞表位。当半抗原是引起中毒的物质时,包含半抗原-载体缀合物的用于固化的组合物对于中毒的治疗特别有用。

版权:(C)2010,日本特许厅&INPIT

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