PROPAGATION OF BOVINE CORONAVIRUS IN CHINESE HAMSTER OVARY CELL

摘要

PROBLEM TO BE SOLVED: To provide improved methods for propagation of BCV (Bovine Corona Virus) in a culture.;SOLUTION: There are provided the methods comprising use of Chinese hamster ovary (CHO) cells for the propagation of coronavirus (including bovine coronavirus) in anchorage-dependent culture and in suspension culture. The BVC VR874 is cultured, in one embodiment, in CHO-K1 cells under conditions in which the virus propagates. The method for propagating the VCB includes a process of culturing the virus in CHO-K1 cells under conditions in which the bovine coronavirus VR-874 virus propagates.;COPYRIGHT: (C)2010,JPO&INPIT