Method for providing a temperature-stable muscle relaxant based on the neurotoxic component of botulinum toxin

摘要

The present invention provides a method for providing a muscle relaxant, wherein said muscle relaxant is a reconstituted solution comprising the neurotoxic component of botulinum toxin free of complexing proteins, which exhibits at least one of the following characteristics, more preferably all characteristics a) to d): a. Stable at storage temperatures above 20° C. b. Stable in the presence of preservatives and/or analgesics c. Resistant against "freeze and thaw"-cycles d. Stable if stored in containers of different material.