METHOD OF TREATING HORMONAL DEFICIENCY IN WOMEN UNDERGOING ESTROGEN REPLACEMENT THERAPY

摘要

PPROBLEM TO BE SOLVED: To provide a pharmaceutical composition that alleviates endometrial hyperplasia, a side effect of estrogen replacement therapy for women. PSOLUTION: The pharmaceutical composition contains an estrogen compound of therapeutically effective amount, a non-aromatizing androgenic compound of a therapeutically effective amount and a pharmaceutically acceptable carrier. The estrogen compound is selected from estrone, 17-estradiol, 17-estradiol, equilin, 17-dihydroequilin, 17-dihydroequilin, equilenin, 17-dihydroequilenin, 17-dihydroequilenin, 8,9-dehydroestrone, 17-8,9-dehydroestradiol, 17-8,9-dehydroestradiol, ethynylestradiol and the like. The non-aromatizing androgenic compound is selected from oxandrolone, oxymetholone, stanozolol, danazol and the like. PCOPYRIGHT: (C)2010,JPO&INPIT