Recombinant mycobacterial strain expressing mycobacterial FAP protein under the control of a promoter active under hypoxia and its application for cancer therapy

摘要

The invention relates to a recombinant vector comprising a polynucleotide fragment encoding a mycobacterial FAP protein under the transcriptional control of a promoter active under hypoxia conditions and its use for the prevention and the treatment of epithelial tumors.