COMPOSITION AND METHOD FOR DETERMINING METASTASIS OF ESOPHAGEAL CANCER

摘要

PROBLEM TO BE SOLVED: To provide a polynucleotide useful for the diagnosis of esophageal cancer metastasis.;SOLUTION: A composition for esophageal cancer diagnosis comprises two or more polynucleotides selected from the group consisting of a polynucleotide having recognizable change in the expression level of esophageal cancer cells with metastasis compared with esophageal cancer cells free from metastasis, its mutant, its fragment, a polynucleotide including a specific base sequence or its complementary sequence, its mutant, its fragment containing 15 or more of consecutive bases, a polynucleotide hybridizing with either one of the polynucleotides under a stringent condition, and its fragment. Further provided are a kit, a DNA chip, and a method for detecting or estimating the metastasis of esophageal cancer by using the composition, kit, or DNA chip.;COPYRIGHT: (C)2010,JPO&INPIT